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The combination of Saccharomyces boulardii and MOS (Mannan Oligosaccharides) provides enhanced support to the intestinal tract and assists gut immune response against undesirable bacteria. MOS directly block bacterial attachment to the epithelial cells of the intestine and reduce their proliferation.
Mannan oligosaccharides contain cell wall fragments obtained from Saccharomyces cerevisiae. Yeast cells are fractured (lysed) and the resulting culture is centrifuged to concentrate mannan oligosaccharides (bound or unbound to proteins) along with beta- glucans. The components then are washed and spray dried.
Mannans have specific structures that are recognized by immune cells. They exist on the cell surfaces or membranes as the primary antigenic or immune- reactive components of whole yeast cells and cell walls. Many pathogenic (gram-negative) bacteria attach to the intestinal wall surface (epithelium) using mannose-specific attachments. MOS provides competitive binding sites for these intestinal pathogens, which is to say that the pathogens attach to the MOS rather than to the intestinal wall surface. Inasmuch as MOS is not digested in the small intestine, bacteria bound to MOS most likely remain attached to these yeast products as they pass through the gut and leave the intestine without attaching to the epithelium. Mannan oligosaccharides may also enhance health by stimulating antibody production or by affecting other intestinal functions
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